Dr. Onur Tigli 
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RESEARCH
The CMOS-SAW© biosensor microchip being probed via GSG configured microprobes. Size of each pad : 100 µm x 100 µm


Research Interests

Nanotechnology

Biosensors

CMOS-MEMS/NEMS

Digital Design ASIC/FPGA




Current Projects

Acoustic Wave Based Cancer Interrogation

CMOS Energy Harvester

Nanowire FET Biosensor

Microfluidics / Lab on a Chip

"If I have seen further it is by standing on the shoulders of giants."

- Isaac Newton





























"All truths are easy to understand once they are discovered; the point is to discover them."

- Galileo Galilei

Interests

Nanotechnology
As a natural extension of the knowledge and experience developed by working in the MEMS and semiconductor fields for many years, we are currently working in the general field of nanotechnology. We are currently working on fabrication of ZnO nanowires and nanobelts as well as the methods to utilize these structures as biosensors.

Biosensors
As the choice of application, we are primarily interested in biosensor development employing MEMS/NEMS technologies. A biosensor is an analytical device containing an immobilized biological sensitive material in contact with or integrated within a transducer, which ultimately converts a biological signal into a quantitatively measurable electrical signal. Sensitivity and selectivity of a biosensor strongly depends on the used immobilization technique. Therefore, alongside with the development of innovative transducer mechanisms, we are also working on a variety of immobilization techniques such as avidin-biotin based immobilization, DNA-protein interaction based biosensing, and self assembled monolayer(SAM) based molecular recognition.

CMOS-MEMS/NEMS
There is an ever growing interest and research for the synthesis and growth of nanoscale devices. However, there is still a big need for designing, fabricating and testing them by reproducible fabrication methods. For this purpose, CMOS technology presents a highly reliable, well established, cost effective platform for integration. We are currently working on integrating nanowires into conventional CMOS technology for sensor applications as a possible solution to this need.

Digital Design
Our primary interest in this field is to utilize the strengths of HDL design entry/synthesis and FPGAs in developing evolvable hardware component libraries for applications in telecommunications, DSP, cryptography, networking, and microprocessor design. We are primarily interested in the introduction of the evolvability aspect (based on genetic algorithms) at behavioral, RTL coding, logic synthesis (gate array cell level), or in physical layout through localized evolution engines.


Current Projects

Acoustic Wave Based Cancer Interrogation

Microscope Image of Fabricated IDTs

FEM Simulation of a SAW

SEM Image of Immobilized Cells

S21 Measured from a SAW Device

This material is based upon work supported by the National Science Foundation CAREER program.

Microfluidics / Lab on a Chip

3D Model of a Cell Covered with Beads

PDMS Microfluidic Channels

Fluorescence Microscopy of Microfluidic Test Structures

Microscope Image of a Patterned Microchannel

This material is based upon work supported by the National Science Foundation CAREER program.

CMOS Energy Harvester

3D FEM Model of a Cantilever Type Energy Harvester

Electrical Potential on a Bent IDT Type Cantilever

SEM Image of Half-Suspended Cantilevers

Mini-Shaker Characterization Test Setup


Nanowire FET Biosensor

3D Model of a Nanowire FET

Nanowire FET Sensing Mechanism

SEM Image of a Fabricated ZnO Nanowire Group

SEM Image and FEM Model of a Single ZnO Nanowire